Medications that May Cause Kidney Damage

Kidney health is vital for overall well-being, yet certain medications, while beneficial for treating various conditions, can pose risks to kidney function. It’s crucial to be aware of these medications, especially if you have pre-existing kidney issues or other risk factors. This post highlights some common medications that may cause kidney damage and offers guidance on how to approach this issue.

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

NSAIDs, such as ibuprofen and naproxen, are widely used for pain relief and inflammation control. However, they can reduce blood flow to the kidneys and lead to kidney damage, particularly when used regularly or in high doses.


Certain antibiotics can be nephrotoxic, particularly if used frequently or in individuals with pre-existing kidney conditions. Examples include aminoglycosides and vancomycin.

ACE Inhibitors

ACE inhibitors, such as lisinopril, are used for hypertension and heart failure. They can cause changes in kidney function, particularly in those with existing kidney issues or dehydration.


Diuretics, often used in treating hypertension and edema, can lead to dehydration, impacting kidney function. Loop diuretics, like furosemide, are particularly known for this risk.

Chemotherapy Drugs

Certain chemotherapy drugs can be toxic to the kidneys. Cisplatin, a common chemotherapy medication, is one such example.

Contrast Dyes Used in Imaging

Contrast dyes used in some imaging tests can affect kidney function, particularly in those with pre-existing kidney conditions.

What Can You Do?

  1. Consult Your Healthcare Provider: Always discuss your medications and potential risks with your healthcare provider, especially if you have kidney disease or other risk factors.
  2. Regular Monitoring: If you’re taking any of these medications, regular kidney function tests can help monitor any changes.
  3. Stay Hydrated: Proper hydration is essential, especially when taking medications that can affect kidney function.
  4. Seek Alternatives: If you are at risk, ask your doctor about safer medication alternatives.
  5. Use Prescription Savings Wisely: If you’re prescribed any of these medications, consider using RxGo to find the best prices and coupons for your prescriptions.

Remember, while this list includes common medications that may impact kidney health, it’s not exhaustive. Always consult with your healthcare provider for personalized advice and before making any changes to your medication regimen. Stay informed and proactive in managing your health.

Note: The information provided in this article is for educational purposes only and should not be substituted for professional medical advice. Always consult with your healthcare provider for personalized guidance and treatment options.